Fabrizia Mealli: Causal Inference when Intervention Units and Outcome Units Differ

When and Where

Thursday, March 12, 2026 11:00 am to 12:00 pm
Room 9014
9th Floor, Ontario Power Building
700 University Ave., Toronto, ON M5G 1Z5

Speakers

Fabrizia Mealli, European University Institute

Description

Causal Inference when Intervention Units and Outcome Units Differ

We study causal inference in settings characterized by interference with a bipartite structure. There are two distinct sets of units: intervention units to which an intervention can be applied and outcome units on which the outcome of interest can be measured. Outcome units may be affected by interventions on some, but not all, intervention units, as captured by a bipartite graph. Examples of this setting can be found in analyses of the impact of pollution abatement in plants on health outcomes for individuals, or the effect of transportation network expansions on regional economic activity. We introduce and discuss a variety of old and new causal estimands for these bipartite settings. We do not impose restrictions on the functional form of the exposure mapping and the potential outcomes, thus allowing for heterogeneity, non-linearity, non-additivity, and potential interactions in treatment effects. We propose unbiased weighting estimators for these estimands from a design-based perspective, based on the knowledge of the bipartite network under general experimental designs. We derive their variance and prove consistency for increasing number of outcome units. Using the Chinese high-speed rail construction study, analyzed in Borusyak and Hull [2023], we discuss non-trivial positivity violations that depend on the estimands, the adopted experimental design, and the structure of the bipartite graph. Joint work with Georgia Papadogeorgou, Zhaoyan Song, and Guido Imbens.

 

Image of Fabrizia Mealli

BIO: Fabrizia Mealli is Professor of Econometrics and Statistics at the Department of Economics, European University Institute, on leave as Professor of Statistics at the University of Florence. She held visiting positions at the Harvard Statistics and Biostatistics Departments. Her research focuses on statistical and econometric methods for causal inference in experimental and observational settings, estimation techniques, simulation methods, missing data, and Bayesian inference, with applications to the social and biomedical sciences. She is an Elected Fellow of the American Statistical Association and past-President of the Society for Causal Inference; she sits on the Steering Committee of the European Causal Inference Meeting (EUROCIM) and Online Causal Inference Seminars (OCIS). She is an Associate Editor for Biometrika, the Journal of the American Statistical Association T&M, The Annals of Applied Statistics, and Observational Studies. Since 2001, Mealli has been teaching Causal Inference in International Schools and in Master and PhD programmes around the world.